What is GeneCodis

GeneCodis is a grid-based tool that integrates different sources of biological information to search for biological features (annotations) that frequently co-occur in a set of genes and rank them by statistical significance. It can be used to determine biological annotations or combinations of annotations that are significantly associated to a list of genes under study with respect to a reference list. GeneCodis executes the following workflow:

Why use GeneCodis?

Most of the currently available tools are designed to evaluate single annotations and they provide a list of annotations with their corresponding p-values without taking account the potential relationships among them. Finding relationships among annotations based on co-occurrence patterns can extend the understanding of the biological events associated to a given experimental system.

What is new in this version?

GeneCodis 2.0 includes a new and faster rule discovery algorithm based on well-known apriori algorithm. This new algorithm let reduce the minimum support needed to expand the range of results available. The whole system is running in a multi-grid environment that allow us to handle simultaneous queries from different users in less time. Moreover, GeneCodis 2.0 includes new funcionalities like searching for simple annotations related to the list of genes, visualizations, new annotations and more gene identifiers are supported.